Association of prepregnancy to early adolescence maternal smoking with young adult mental health

Abstract

Objective: Maternal smoking across pregnancy and childhood is associated with adverse mental health outcomes in offspring. Few studies have prospectively examined this association using administrative data. This study investigated whether maternal smoking from prepregnancy through the child’s early adolescence (age 13 years) was associated with mental health disorders in young adult offspring.

Methods: Using a population-based longitudinal cohort with linked administrative health data, maternal smoking status was assessed at multiple time points from prepregnancy through the child’s early adolescence. Mental health outcomes in young adulthood were ascertained from administrative records. Associations were estimated using regression models with appropriate adjustments for potential confounders.

Results: Maternal smoking exposure across the prepregnancy to early adolescence period was associated with increased risk of mental health disorders in young adult offspring. Dose-response patterns by duration and timing of exposure were examined.

Conclusions: These findings underscore the long-term mental health consequences of sustained maternal smoking exposure for offspring and support public health efforts to promote smoking cessation among women of childbearing age and throughout childhood.

Citation recommandée : Legault, O., Collet, O., Martínez, P., Côté, S. M., et al. (2026). "Association of prepregnancy to early adolescence maternal smoking with young adult mental health." Pediatrics Open Science. 2(2).
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